FEWER ACHES. FASTER HEALING. SLOWER AGING.
New Joint combines pain relieving, anti-aging, anti-inflammatory compounds with a cartilage and bone repair formula for powerful results you'll actually feel working- in just days.*
The supplement of choice for people who need to be active everyday.
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3 Bottles
180 capsules
$94.99
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Unique Ingredients
Just 2 capsules per day provide same-day relief and long term anti-aging joint support.
Results are rapid, but you must take New Joint consistently for 90 days in order to get the full benefits of this powerful product.
Simple Yet Powerful: 5 Active Ingredients
The benefits of New Joint are unlike anything you've tried before. It contains only 5 natural and plant-based ingredients that provide powerful relief with no unpleasant side effects and a clinically effective doses in just two capsules per day!
Quadraflex® Cissus Quandrangularis Stem Extract
Cissus quadrangularis is the powerhouse pain relieving plant that is the basis of New Joint. This strange looking "succulent vine" is native to India and has been used there for a few thousand years in traditional Ayurvedic medicine.
It's in the grape family and is known traditionally as 'bone setter' due to its fracture healing properties.
It has a lot of benefits. The ones you'll feel with your first dose are the pain relieving and muscle relaxing properties, which make New Joint great for everything that hurts.
Equally important are its anti-inflammatory properties. More specifically, for those fellow nerds, it inhibits COX enzymes as well as many other pro-inflammatory mediators.
Most interesting, studies show Cissus helps build new cartilage, bone, and collagen. To really get into the nitty gritty biology, it stimulates cells of mesenchymal origin- fibroblasts; which make collagen, chondroblasts; which form cartilage matrix, and osteoblasts; which form new bone.
Finally, it's a potent antioxidant and protects the stomach lining from ulcers in rodents exposed to high-dose aspirin.
Quadraflex® Cissus extract is a 10% ketosterone extract that has been optimized for joint health. In short, we used the best, most effective Cissus quadrangularis extract available.
New Joint contains 1,300 mg per 2 capsules.
MenaQ7® Vitamin K2 MK-7 + Vitamin D3 Complex
Vitamin MK7 K2 is found only in fermented foods, so most people are sorely deficient in this critical nutrient. Combined with Vitamin D3, this pair offers true synergy- combined they produce more valuable effects than they can alone!
Over the past decade, much research has come out about vitamin K2 and its benefits on the body as a whole. Newer studies show the synergistic effect of both D3 and K2 have a major impact increasing bone density, improving joint function and reducing the risk of heart disease.
Finally, this combination is designed to help support the immune system and healthy inflammation levels. It even supports an even, regular mood and may improve memory and cognition!
As we get older, stay indoors more, and wear sunscreen, our Vitamin D levels can drop dangerously low, and this is associated with serious long term health problems and chronic illness.
Vitamin D is crucial for lifelong healthy aging and New Joint keeps your levels just right.
Vitamin C
Getting the right amount of vitamin C is key for both preventing inflammation from arthritis and maintaining healthy joints.
A growing body of research suggests Vitamin C may ease pain, reduce inflammation, and protect against cartilage damage.
Vitamin C is a powerful antioxidant that fights joint inflammation. It also serves as a co-factor in collagen synthesis, the main protein in joint tissue and bone.
In fact, a 2019 study published in the journal Arthritis Care & Research found vitamin C may protect against knee damage in people with osteoarthritis.
Bioperine® Piper Nigrum derived piperine
This extract of the vining Piper nigrum berry boosts your stomachs ability to absorb nutrients.
This means you get more active ingredients into your body out of a smaller dose of New Joint so you can take fewer capsules!
Piperine is also a potent anti-inflammatory on its own and enhances the joint relieving performance of New Joint!
What It Doesn't Have
We only put clinically proven active ingredients in New Joint, which means smaller capsules and no junk!
1No Gluten or Common Allergens
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2No Shellfish or Animal Products
3No Fillers or Food Dyes
Real Reviews from Long-Time Customers
Our customers love this product because they see results fast- usually within two weeks or less!
This really works. I don't have as much arthritis pain as I did before taking it. I won't run out of it. I'm so happy to have found this.
-SB
I've tried a lot of things short of knee replacement including acupuncture, which provides some temporary relief, and this is the first time I feel something is really working!
-Tam, Marin County, CA
Starting using New Joint about a month ago. Marked improvement in a short amount of time. So glad to finally find a vegan option for joint pain. Will continue to use it.
Thanks for a great product.-N. Combs, Dahlonega, GA
This is the best natural pain reliever I have found so far. I have been able to reduce my ibuprofen use (to once every other day) and I am more active than I have been in years.
-Gabe TieldenMy knees and hands feel better now, better than they ever have. These are small and much easier to swallow than the glucosamine/chondroitin horse pills, and its nice to only take two for these kind of results. I also like the idea of long term repair with these, so we'll see if that is the case. I'll be ordering again.
-Marisa Marcek
I have tried many supplements for my joint pain and New Joint is the only one that has helped with the terrible pain I have in my knees. Thanks to New Joint I can get out and walk my jobsites much easier.
-Abraham Fernandez
The Research
The ingredients in New Joint™ have been the subject of hundreds of research studies and trials. We've compiled some of them below for your convenience.
MenaQ7® Vitamin K2 MK-7
1.IThe Relationship between Vitamin K and Osteoarthritis: A Review of Current Evidence. Kok-Yong Chin. Nutrients. 2020 May; 12(5): 1208.
2. Vitamin K as a Powerful Micronutrient in Aging and Age-Related Diseases: Pros and Cons from Clinical Studies. Fusaro M, et al. Int J Mol Sci. 2019 Sep; 20(17): 4150.
M H J Knapen, N E Drummen, E Smit, C Vermeer, E Theuwissen. Osteoporos Int . 2013 Sep;24(9):2499-507.
4. Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases. Dina C. Simes, et. al. Nutrients. 2020 Jan; 12(1): 138.
5. Sufficient vitamin K status combined with sufficient vitamin D status is associated with better lower extremity function: a prospective analysis of two knee osteoarthritis cohorts. M. Kyla Shea, et al. Arthritis Care Res (Hoboken). 2018 Aug; 70(8): 1150–1159.
6. Vitamin K and Osteoporosis. Fusaro M, et al. Nutrients. 2020 Dec; 12(12): 3625.
7. Vitamin K Deficiency Is Associated with Incident Knee Osteoarthritis. Devyani Misra, et al. American Journal of Medicine. 2013 Mar; 126(3): 243–248.
8. MK-7 and Its Effects on Bone Quality and Strength. Toshiro Sato, Naoko Inaba, and Takatoshi Yamashita. Nutrients. 2020 Apr; 12(4): 965.
9. Vitamin K2 Holds Promise for Alzheimer’s Prevention and Treatment. Alexander Popescu and Monica German. Nutrients. 2021 Jul; 13(7): 2206.
10. Relationship Amongst Vitamin K Status, Vitamin K Antagonist Use and Osteoarthritis: A Review. Kok-Yong Chin et al. Drugs & Aging. 2022 Jul;39(7):487-504.
Cissus Quadrangularis
1. Cissus quadrangularis reduces joint pain in exercise-trained men: a pilot study. Bloomer RJ, Farney TM, McCarthy CG, Lee SR. Phys Sportsmed. 2013 Sep;41(3):29-35.
Bhujade AM, Talmale S, Kumar N, Gupta G, Reddanna P, Das SK, Patil MB. J Ethnopharmacol. 2012 Jun 14;141(3):989-96.
Kothari SC, Shivarudraiah P, Venkataramaiah SB, Koppolu KP, Gavara S, Jairam R, Krishna S, Chandrappa RK, Soni MG.
Food Chem Toxicol. 2011 Dec;49(12):3343-57.
4. Efficacy and Safety of Cissus quadrangularis L. in Clinical Use: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Sawangjit R, Puttarak P, Saokaew S, Chaiyakunapruk N. Phytother Res. 2017 Apr;31(4):555-567.
5. A review and evaluation of the efficacy and safety of Cissus quadrangularis extracts. Stohs SJ, Ray SD.
Phytother Res. 2013 Aug;27(8):1107-14.
Jadhav AN, Rafiq M, Devanathan R, Azeemuddin M, Anturlikar SD, Ahmed A, Sundaram R, Babu UV, Paramesh R.
Pharmacogn Mag. 2016 May;12(Suppl 2):S213-7.
7. Ethanol Extract of Cissus quadrangularis Enhances Osteoblast Differentiation and Mineralization of Murine Pre-Osteoblastic MC3T3-E1 Cells. Tasadduq R, Gordon J, Al-Ghanim KA, Lian JB, Van Wijnen AJ, Stein JL, Stein GS, Shakoori AR.
J Cell Physiol. 2017 Mar;232(3):540-547.
Brahmkshatriya HR, Shah KA, Ananthkumar GB, Brahmkshatriya MH. Ayu. 2015 Apr-Jun;36(2):169-73.
9. Cissus quadrangularis attenuates the adjuvant induced arthritis by down regulating pro-inflammatory cytokine and inhibiting angiogenesis. Kumar R, Gupta YK, Singh S, Arunraja S. J Ethnopharmacol. 2015 Dec 4;175:346-55.
10. Evaluation of anti-inflammatory activity of selected medicinal plants used in Indian traditional medication system in vitro as well as in vivo. Shaikh RU, Pund MM, Gacche RN. J Tradit Complement Med. 2015 Aug 1;6(4):355-361.
11. Cissus quadrangularis inhibits IL-1β induced inflammatory responses on chondrocytes and alleviates bone deterioration in osteotomized rats via p38 MAPK signaling. Kanwar JR, Samarasinghe RM, Kumar K, Arya R, Sharma S, Zhou SF, Sasidharan S, Kanwar RK. Drug Des Devel Ther. 2015 Jun 5;9:2927-40.
12. Involvement of opioidergic and serotonergic systems in the analgesic activity of Cissusquadrangularis L. stem extract in mice. Nie TW, Shukkoor MS, Nair RS, Amiruddin FK, Ramasamy S. J Basic Clin Physiol Pharmacol. 2015 Jan;26(1):35-41.
13. Analgesic, anti-inflammatory and venotonic effects of Cissus quadrangularis Linn. Panthong A, Supraditaporn W, Kanjanapothi D, Taesotikul T, Reutrakul V. J Ethnopharmacol. 2007 Mar 21;110(2):264-70
14. Gastroprotective action of Cissus quadrangularis extract against NSAID induced gastric ulcer: role of proinflammatory cytokines and oxidative damage. Jainu M, Devi CS. Chem Biol Interact. 2006 Jul 10;161(3):262-70.
Vitamin D3
Manoy P, Yuktanandana P, Tanavalee A, Anomasiri W, Ngarmukos S, Tanpowpong T, Honsawek S. Nutrients. 2017 Jul 26;9(8). pii: E799
2. Vitamin D in Pain Management. Helde-Frankling M, Björkhem-Bergman L. Int J Mol Sci. 2017 Oct 18;18(10). pii: E2170.
3. Longitudinal Associations of Serum 25-hydroxyvitamin-D, Physical Activity, and Knee Pain and Dysfunction with Muscle Loss in Community-dwelling Older Adults. Balogun S, Aitken D, Winzenberg T, Wills K, Scott D, Callisaya M, Jones G.
J Gerontol A Biol Sci Med Sci. 2017 Aug 14.
4. The effect of vitamin D status on pain, lower limb strength and knee function during balance recovery in people with knee osteoarthritis: an exploratory study. Levinger P, Begg R, Sanders KM, Nagano H, Downie C, Petersen A, Hayes A, Cicuttini F.
Arch Osteoporos. 2017 Sep 23;12(1):83.
5. Association between serum vitamin D levels and neuropathic pain in rheumatoid arthritis patients: A cross-sectional study. Yesil H, Sungur U, Akdeniz S, Gurer G, Yalcın B, Dundar U. Int J Rheum Dis. 2017 Aug 31.
Panwar A, Valupadas C, Veeramalla M, Vishwas HN. Clin Rheumatol. 2017 Aug 25.
Yong WC, Sanguankeo A, Upala S. Clin Rheumatol. 2017 Aug 15.
Gao XR, Chen YS, Deng W. Int J Surg. 2017 Oct;46:14-20.
Englund M, Persson J, Bergström I. Int J Circumpolar Health. 2017;76(1):1340547.
Hung M, Bounsanga J, Voss MW, Gu Y, Crum AB, Tang P. J Nutr Gerontol Geriatr. 2017 May 30:1-13.
11. Maintaining Vitamin D Sufficiency Is Associated with Improved Structural and Symptomatic Outcomes in Knee Osteoarthritis. Zheng S, Jin X, Cicuttini F, Wang X, Zhu Z, Wluka A, Han W, Winzenberg T, Antony B, Aitken D, Blizzard L, Jones G, Ding C. Am J Med. 2017 Oct;130(10):1211-1218.
12. Do vitamin D levels affect the clinical prognoses of patients with knee osteoarthritis?
Alkan G, Akgol G. J Back Musculoskelet Rehabil. 2017;30(4):897-901.
13. Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis. Wang X, Cicuttini F, Jin X, Wluka AE, Han W, Zhu Z, Blizzard L, Antony B, Winzenberg T, Jones G, Ding C.
Osteoarthritis Cartilage. 2017 Aug;25(8):1304-1312.
About Wellness Research Group, LLC
New Joint was formulated by a Registered Dietitian Nutritionist (RDN) whose dad was suffering from serious side effects as a result of his daily pain relief regimen of prescription NSAID pain relievers for his joint pain. Within a few weeks of taking the first prototype of New Joint, he was able to discontinue his daily pharmaceutical pain relievers, get greater joint comfort and relief, and totally eliminate his painful gastrointestinal side effects. With the help of pharmacist, physician, and nutrition industry advisers, Wellness Research Group was created and New Joint was released to the public. Since then, thousands of customers have found relief they didn't think was possible from a dietary supplement.
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Any statements on this site or any materials or supplements distributed or sold by www.newjoint.us have not been evaluated by the Food and Drug Administration.
FruiteX-B® products are protected by US patents 5962049, 6696419, and 6924269, issued foreign patents, and pending US and foreign applications. FruiteX-B® is a registered trademark of VDF FutureCeuticals, Inc. used under license.